Lipid Nanoparticle Process Development Scientist

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.The candidate will have a highly visible and integral role towards the process development, scale-up, and manufacturing of Gene Therapy LNPs. The ideal candidate will have experience with lipid nanoparticle formulation, various mixing equipment, TFF system, characterization tools and understanding/knowledge of process parameters. In this highly collaborative and cross functional role, you will help develop/optimize the client process and improve process understanding for multiple programs at various stages of non-clinical development.Job Responsibilities

Support scale up development and optimization of LNP drug product formulation processes and storage form development for gene therapies

Provide formulation support for non-GLP large animal studies.

Work with cross functional teams to support process transfer, scale-up, and resolving process trouble shootings.

Formulate and characterize LNPs for preclinical studies internal and external to support consistency and high-quality readout across batches and stability evaluations.

Maintain records of all relevant data in the electronic laboratory notebook system, hard cover recording (batch record) and present findings to client project teams.

Contribute SOP, batch records, report, campaign summary reports, etcs.

Other duties as assigned.

Master’s degree in chemistry, chemical engineering, biomedical engineering, or related fields with 2+ years of relevant industrial working experience preferred. Alternatively, a bachelor’s degree in chemistry, chemical engineering, biomedical engineering, or related fields with 4+ years of recent relevant industrial working experience.

Experience in LNP formulation (NanoAssemblr) and nanoparticle characterization

Understanding engineering of process development, scale-up, manufacturing, and tech transfer

Experience with analytical methods (DLS, UV/VIS, Osmo, pH, etcs) for LNP characterization.

Experience with large-scale LNP formulation (T-mixing, IJM) and TFF processes.

Authorization to work in the United States indefinitely without restriction or sponsorship

Position is full-time. Candidates currently living within a commutable distance of Boston, MAare encouraged to apply Excellent full-time benefits including comprehensive medical coverage, dental, and vision options.

Excellent full-time benefits including comprehensive medical coverage, dental, and vision options

Life and disability insurance

401(k) with company match

Paid vacation and holidays

Eurofins is aM/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.