Executive Director, Translational Modeling

Job Description The department of Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) is seeking an Executive Director to lead the Translational Modeling team within the Translational Sciences and Outsourcing (TSO) organization.The Translational Modeling Executive Director will have broad responsibilities encompassing the pipeline, talent development and strategy, and will be responsible for driving application of our quantitative capabilities in the areas of translational PK/PD, data science and toxicokinetics. These efforts are intended to enable earlier and more confident decision making around PK/PD, therapeutic window, modality selection, clinical readiness and dose prediction across all therapeutic areas for small molecule, peptide and protein therapeutics.The successful candidate will also contribute to the alignment of departmental and portfolio priorities within the company’s strategic framework. To achieve this, they will lead a team of talented scientists and partner with cross-functional stakeholders, and be responsible for talent development and performance management of their staff.As a member of the TSO Leadership Team, the Executive Director will contribute to global scientific and portfolio strategy across TSO and the broader PDMB organization. They are expected to demonstrate exemplary ways of working, strong ethics, good negotiation skills and an enterprise mindset.The Translational Modeling Executive Director role will be responsible for providing strategic leadership and talent management for the group through:

Leading a team of >15 scientists and group leaders including people management, scientific and operational oversight, under the direction of the Associate Vice President of TSO

Leveraging drug discovery, data science, translational and disease area expertise to set scientific strategy and provide scientific oversight to identify and optimize drug candidates with a focus on both efficacy and safety

Supporting the diversity of our teams, ensuring equity of opportunity and an inclusive workplace

Identifying resource needs and contributing to resource allocation internally and through management of business operations including travel and outsourcing budgets

Working with TSO leadership to contribute to the development and execution of departmental priorities and ensure broad alignment of individual priorities/ performance of the team with the TSO and larger PDMB vision and mission. As a member of the PDMB extended leadership team, contribute to strategic discussions and execution of PDMB priorities

Providing functional representation on governance committees, task forces or initiatives

Education: PhD or equivalent degree with at least 10 years of drug discovery or development experience or MS/ PharmD with at least 13 years of experience.Required Experience and Skills:

A record of both internal and external impact in driving model-informed drug discovery and translational PK/PD strategies

Demonstrated track record in establishing an inclusive and high-performance work environment through building talent, fostering collaboration, driving results and managing teams to drive innovation and scientific excellence

Experience in performing hands-on translational PK/PD modeling for small molecules and protein therapeutics

Established leader in the field of translational sciences with a track record of external visibility through publications, presentations and/or involvement in professional organizations

Preferred Experience and Skills:

Experience with applying data science approaches such as AI/ML in drug discovery and development to enable AI-driven MIDD

Familiarity with the application of quantitative approaches to inform toxicokinetic/toxicodynamic relationships and the assessment of therapeutic window

Current Employees apply HERE (https://wd5.myworkday.com/msd/d/task/1422$6687.htmld) Current Contingent Workers apply HERE (https://wd5.myworkday.com/msd/d/task/1422$4020.htmld) US and Puerto Rico Residents Only: Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here (https://survey.sogosurvey.com/r/aCdfqL) if you need an accommodation during the application or hiring process.We are an Equal Opportunity Employer, committed to fostering an inclusive and diverse workplace. All qualified applicants will receive consideration for employment without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status, or other applicable legally protected characteristics. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:EEOC Know Your Rights (https://www.eeoc.gov/sites/default/files/2022-10/22-088EEOCKnowYourRights1020.pdf) EEOC GINA Supplement Pay Transparency Nondiscrimination (https://www.dol.gov/sites/dolgov/files/OFCCP/pdf/pay-transp%20EnglishformattedESQA508c.pdf) We are proud to be a company that embraces the value of bringing diverse, talented, and committed people together. The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts (https://www.msdprivacy.com/us/en/CCPA-notice/) U.S. Hybrid Work Model Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence.This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as “remote”.The Company is required to provide a reasonable estimate of the salary range for this job in certain states and cities within the United States. Final determinations with respect to salary will take into account a number of factors, which may include, but not be limited to the primary work location and the chosen candidate’s relevant skills, experience, and education.Expected US salary range:$243,500.00 - $383,300.00Available benefits include bonus eligibility, long term incentive if applicable, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. A summary of benefits is listed here (https://www.benefitsatmerck.com/) .San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance OrdinanceLos Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring OrdinanceSearch Firm Representatives Please Read CarefullyMerck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails. Employee Status: RegularRelocation: DomesticVISA Sponsorship: YesTravel Requirements: 10%Flexible Work Arrangements: HybridShift: Not IndicatedValid Driving License: NoHazardous Material(s): N/ARequired Skills: Business Intelligence (BI), Database Design, Data Engineering, Data Modeling, Data Science, Data Visualization, Machine Learning, Software Development, Stakeholder Relationship Management, Waterfall Project ManagementPreferred Skills: Job Posting End Date: 11/11/2024A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date. Requisition ID: R318635