Postdoctoral Research Fellow

Postdoctoral Research FellowApply NowHow to ApplyPlease combine the cover letter, CV and references into ONE document before submitting your electronic application. A cover letter is required for consideration of the position, and should address your specific interest in the position, your research accomplishments, and outline your skills and experience that directly relate to this position. The names, institutions, phone numbers and email addresses should be provided for 3 professional references. Any questions related to this position may be addressed to Greg Cartee at: [email protected] .Job SummaryA post-doctoral research fellow position is available at the University of Michigan in the Muscle Biology Laboratory (directed by Greg Cartee; https://www.kines.umich.edu/research/labs-centers/muscle-biology-laboratory ) to elucidate the mechanisms whereby exercise and/or diet regulate glucose uptake and insulin and/or AMPK signaling in skeletal muscle. The laboratory group has extensive expertise in a variety of methods for rigorous study of glucose uptake and signaling in rodent skeletal muscle, including the use of adeno-associated virus (AAV) approaches to manipulate protein expression. In addition to collaborative research with other members of the Muscle Biology Laboratory, the trainee will have the opportunity to interact with an outstanding group of researchers in other labs at the University of Michigan, as well as our collaborators at other institutions. There will be opportunities for career development, including participating in the preparation and submission of research grants.The publications listed below are relevant to ongoing research in the Muscle Biology Laboratory.

Wang, H., A. Zheng, E.B. Arias, S.E. Kwak, X. Pan, D. Duan, and G.D. Cartee. AS160 expression, but not AS160 Serine-588, Threonine-642, and Serine-704 phosphorylation, is essential for elevated insulin-stimulated glucose uptake by skeletal muscle from female rats after acute exercise. FASEB J. 37(7):e23021, 2023. PMID: 37289137

Kwak, S.E., A. Zheng, H. Wang, E.B. Arias, X. Pan, Y. Yue, D. Duan, and G.D. Cartee. A novel genetic model provides a unique perspective on the relationship between postexercise glycogen concentration and increases in the abundance of key metabolic proteins after acute exercise. PLoS One. 2024 Jan 30;19(1):e0295964. doi: 10.1371/journal.pone.0295964. eCollection 2024. PMID: 38289946

Zheng, A., S.E. Kwak, J.B. Birk., E.B. Arias, D. Thorley, J.F.P. Wojtaszewski, and G.D. Cartee. Greater phosphorylation of AMPK and multiple AMPK substrates in the skeletal muscle of 24 month-old calorie restricted compared to ad libitum fed male rats. J. Gerontol. A Biol. Sci. Med. Sci. 78(2):177-185, 2023. PMID: 36269629

Required QualificationsThe individuals must have a Ph.D. (or M.D. / D.V.M.) degree in a biological science. The candidates must have a high level of motivation for applying cell biology, molecular biology, biochemical, and/or physiological approaches to research performed using rodent models. The ideal applicant will have knowledge, experience, and technical skill with cellular, molecular, biochemical, and/or physiological methods to complement the ongoing research in the Muscle Biology Laboratory. Effective verbal and written communication are important. The successful candidate will be able to work independently and as a member of a research team. Must have proven success with contributing to a positive workplace culture, and ability to consistently demonstrate our school'score values. (https://www.kines.umich.edu/about/mission-values-leadership)Desired QualificationsExperience with siRNA, shRNA, and/or adeno-associated virus (AAV) methods in cells or tissues in vivo would be useful. Experience with fractionation of tissue, especially skeletal muscle, by various methods to enable analysis of different subcellular fractions would be helpful. Experience with confocal and/or light microscopy would be useful.Modes of WorkPositions that are eligible for hybrid or mobile/remote work mode are at the discretion of the hiring department. Work agreements are reviewed annually at a minimum and are subject to change at any time, and for any reason, throughout the course of employment. Learn more about the work modeshere (https://dev.hr.umich.edu/working-u-m/my-employment/ways-we-work-resource-center/ways-we-work-implementation-group/modes-work) .Application DeadlineJob openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.U-M EEO/AA StatementThe University of Michigan is an equal opportunity/affirmative action employer.Job DetailJob Opening ID252624Working TitlePostdoctoral Research FellowJob TitleRESEARCH FELLOWWork LocationAnn Arbor CampusAnn Arbor, MIModes of WorkOnsiteFull/Part TimeFull-TimeRegular/TemporaryRegularFLSA StatusExemptOrganizational GroupSchool KinesiologyDepartmentSchool of KinesiologyPosting Begin/End Date8/05/2024 - 9/04/2024Career InterestResearch FellowsApply Now